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SingleCare (formerly FamilyWize) partners with United Way and 211 to help Americans afford much-needed prescription medications so they can live happy, health lives. With prescription savings cards, SingleCare is helping individuals who are uninsured, underinsured, or insured by high deductible plans save up to 80% on prescription medications. Since 2005, SingleCare has helped over 21 million people save more than $2 billion on prescription drug costs.

At the beginning of the COVID-19 pandemic, as 211 call centers were flooded with calls from individuals seeking help with health care needs, trained staff from SingleCare served as volunteers for the 211 "virtual" National Call Center. With the support of the SingleCare volunteers, 211 was able to connect more individuals in need with support and services.

During flu season, SingleCare, in partnership with Walgreens, provides 5,000 Free Flu Shot Vouchers to 211 centers across the nation to help more people get protected against seasonal flu.